The presentation is to draw a picture of Optical Coherence Tomography (OCT), which has tremendous applications in biomedical research and clinic disease diagnosis, with a great potential commercial market. The fundamental principle of the OCT is to use the theory of the coherent optics or the electromagnetic waves. The focus of the OCT study is to get high resolution, high contrast and high imaging speed. I would like to discuss how to improve the performance of OCT, and also to demonstrate a few kinds of OCT images and real time movies collected by the OCT devices developed in the group at Case Western Reserve University. The last topic of this talk will be about the challenges in the field of OCT and also about some other optical imaging technologies, as well as the image enhanced by optics.